BMB Faculty Research

Research in Biochemistry and Molecular Biology at UMass Amherst
Research Areas	Experimental Systems
Cell Cycle Control and Cancer	Drosophila
Developmental Biology	Eukaryotic Cell Culture
Organelle Biogenesis and Development	Plants
Protein Folding and Maturation	Prokaryotic Cell Culture
Protein Synthesis, Structure, and Function	Yeast
RNA Synthesis, Structure, and Function
Signal Transduction

Cell Cycle Control and Cancer

	David Gross Cell surface receptor signaling Lab home page		Molly Fitzgerald-Hayes Centromeres and kinetochores: molecular machines control chromosome movement Lab home page
	Karsten Theis DNA repair, Molecular motors, X-ray crystallography Lab home page		Susan Cumberledge Signal transduction at the neuromuscular junction and regulation of synaptogenesis



Developmental Biology

	Maura Cannon Plant embryogenesis, Polyhydroxyalkanote inclusion bodies		Alice Cheung Signal transduction in vegetative and reproductive development in plants
	Susan Cumberledge Signal transduction at the neuromuscular junction and regulation of synaptogenesis


Organelle Biogenesis and Development

	Danny Schnell Mechanisms of protein import into plant chloroplasts, Protein targeting, Organelle biogenesis


Protein Folding and Maturation

	Scott Garman Structural biology of glycoproteins in human disease		Lila Gierasch Protein folding in the cell Lab home page
	Daniel Hebert Protein folding, quality control and degradation of membrane glycoproteins		Danny Schnell Mechanisms of protein import into plant chloroplasts, Protein targeting, Organelle biogenesis
	Alejandro Heuck Pore-forming toxins and translocation of virulence factors in bacterial pathogenesis. Fluorescence Spectroscopy.


Protein Synthesis, Structure, and Function

	Lila Gierasch Protein folding in the cell Lab home page		Molly Fitzgerald-Hayes Centromeres and kinetochores: molecular machines control chromosome movement Lab home page
	Maurille ("Skip") Fournier Molecular biology of small nucleolar RNAs (snoRNAs), snoRNA biotechnology		Karsten Theis DNA Repair Molecular motors, Xray crystallography Lab home page
	Robert Zimmermann Ribosome assembly and function, Protein-RNA interactions, Protein synthesis		Scott Garman Structural biology of glycoproteins in human disease
	Alejandro Heuck Pore-forming toxins and translocation of virulence factors in bacterial pathogenesis. Fluorescence Spectroscopy.

RNA Synthesis, Structure, and Function

	Maurille ("Skip") Fournier Molecular biology of small nucleolar RNAs (snoRNAs), snoRNA biotechnology		Robert Zimmermann Ribosome assembly and function, Protein-RNA interactions, Protein synthesis
	Karsten Theis DNA Repair Molecular motors, Xray crystallography Lab home page


Signal Transduction

	Susan Cumberledge Signal transduction at the neuromuscular junction and regulation of synaptogenesis		Alice Cheung Signal transduction in vegetative and reproductive development in plants
	Molly Fitzgerald-Hayes Centromeres and kinetochores: molecular machines control chromosome movement Lab home page		David Gross Cell surface receptor signaling Lab home page
	Jennifer Normanly Metabolic regulation and engineering Lab Home Page		Dan Chase Dopamine signaling


Experimental Systems


Drosophila

	Susan Cumberledge Signal transduction at the neuromuscular junction and regulation of synaptogenesis	Additional UMass faculty members using Drosophila as a model system are in the Biology Dept.


Eukaryotic Cell Culture

	Susan Cumberledge Signal transduction at the neuromuscular junction and regulation of synaptogenesis		David Gross Cell surface receptor signaling Lab home page
	Daniel Hebert Protein folding, quality control and degradation of membrane glycoproteins		Dan Chase Dopamine signaling


Plants

	Maura Cannon Plant embryogenesis, Polyhydroxyalkanote inclusion bodies Lab home page		Alice Cheung Signal transduction in vegetative and reproductive development in plants
	Jennifer Normanly Metabolic regulation and engineering Lab Home Page		Danny Schnell Mechanisms of protein import into plant chloroplasts, Protein targeting, Organelle biogenesis


Prokaryotic Cell Culture

	Robert Zimmermann Ribosome assembly and function, Protein-RNA interactions, Protein synthesis		Alejandro Heuck Pore-forming toxins and translocation of virulence factors in bacterial pathogenesis. Fluorescence Spectroscopy.


Yeast

	Molly Fitzgerald-Hayes Centromeres and kinetochores: molecular machines control chromosome movement Lab home page		Maurille ("Skip") Fournier Molecular biology of small nucleolar RNAs (snoRNAs), snoRNA biotechnology

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