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Advanced Technologies for Molecular Research at UMass Amherst |
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These campus facilities and services are available for research and teaching by members of the UMass and Five College communities. The facilities were established and are maintained by combined support from the UMass science departments and the UMass administration. |
| Automated DNA Sequencing Facility |
| The Genomics & Bioinformatics Facility offers automated DNA sequencing services to the academic community at UMass Amherst and the Five Colleges. |
| Biological Computer Resource Center (BCRC) |
| The BCRC's mission is to improve undergraduate learning in the life sciences through instructional technology. The BCRC provides access to a wide range of computer hardware including twenty Power PC workstations are available for student and faculty use. The BCRC also provides assistance with Instructional Technology projects that support undergraduate instruction in the life sciences. |
| Flow Cytometry Facility |
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The cytometry facility contains fluorescence-activated cell sorters (FACS) used for analysis of cell types as distinguished by antigen determinants, cell cycle analysis, and the isolation of defined cell populations for further study. |
| The Central Microscopy Facility |
| The Microscopy Facility provides faculty and students with access to state-of-the-art imaging instruments for research and teaching, including light microscopy, transmission electron microscopy (EM), scanning electron microscopy (SEM) and confocal imaging. Students and faculty can become trained to use the imaging instruments and obtain advice about individual research projects at the microscopy facility. |
| Mass Spectrometry and Molecular Weight Determination |
| The Mass Spectrometry Facility maintains sophisticated instruments for the molecular analysis of complex substances. These include electrospray ion trap with HPLC, MALDI-TOF, high resolution two-sector mass spectrometer and an MS Engine GC-MS system. |
| Phosphorimager |
| The Molecular Dynamics STORM 840 phosphorimager is a multiuser instrument with radioactive and nonradioactive detection capabilities. Researchers can use storage phosphor screen autoradiograpy, direct fluorescence or chemifluorescence for their DNA, RNA, and protein samples. ImageQuant image analysis software runs on a Macintosh platform to analyze data collected by the STORM 840. Densitometers and gel reading software are also available. |
| Spectroscopy Facility |
| The Spectroscopy Facility contains instruments for High Field Nuclear Magnetic Resonance, Vibrational Spectroscopy and X-Ray Photoelectron Spectroscopy. These highly sophisticated instruments are used for the structure determination of macromolecules, including multinuclear, multidimensional NMR analysis of proteins and site-directed studies of insoluble, large systems such as membrane proteins. The facility is operated jointly by the departments of Biochemistry and Molecular Biology, Chemistry and Polymer Science and Engineering. |