BMB Assistant Professor Margaret Stratton, Postdoctoral Researcher Roman Sloutsky, and MCB PhD Candidate Noelle Dziedzic recently published a report in Science Signaling describing their recent findings on the CaMKII protein. Researchers in the Stratton Lab discovered that the organizational center of the CaMKII molecular complex acts like a tuner for calcium sensitivity. This opens-up a whole new area for investigation as researchers continue to learn more about this memory protein.
Stratton Lab discovers new regulatory role for CaMKII protein
Peter Chien publishes findings on how cells keep growing even when under attack
BMB Professor Peter Chien recently published a paper in the Cell journal Molecular Cell describing how bacteria switch gears to respond to different stresses while maintaining normal cell functions. A damage-containment system in stressed bacteria can become overrun and blocked, but that this leads to cells responding by turning on very different pathways to make sure that normal growth continues. Understanding how cells take advantage of protease competition to respond to stress could help us inhibit similar pathways to block uncontrolled growth in cancer cells.
Lila Gierasch, Li-Jun Ma, and Megan West receive CNS Outstanding Achievement Awards
Three members of the BMB community have received 2020 Outstanding Achievement Awards from the College of Natural Sciences (CNS). Distinguished Professor Lila Gierasch and Associate Professor Li-Jun Ma were both recognized for their research, while Director of Administration and Outreach Megan West was celebrated for her commitment to diversity and inclusion. The CNS Outstanding Achievement Awards recognize faculty, staff, and students who have made important contributions to their discipline, department, college and university.
Congratulations and thank-you to BMB Writing Fellow Jenny Krichevsky
Eugenia “Jenny” Krichevsky, founding member of the BMB Writing Fellow program, is moving on to a faculty position at Cal State Fresno. The faculty, staff, and students of the BMB Department want to thank Jenny for all she has done for the campus and BMB writing programs and all our majors. We wish her much success in the future!
Tricia Serio discovers breakthrough for curing fatal diseases caused by prions
Tricia Serio, Dean of the College of Natural Sciences and Professor in the Biochemistry and Molecular Biology department, recently published a paper in Nature Structural and Molecular Biology describing a breakthrough she hopes could lead to a cure for group of fatal diseases caused by prions. She and her team believe controling the transformation of the nucleation seed complex that forms when prions attach to one another is the key to stopping the disease from arising.
Daniela Molina Palacios (BMB Class of 2020) honored as a 21st Century Leader
Daniela Molina Palacios, a Biochemistry and Molecular Biology student and a member of the Commonwealth Honors College, is one of ten graduating seniors who have been selected as 21st Century Leaders. This honor is given to seniors who exhibit exemplary achievement, initiative, and leadership. A native of Venezuela, Daniela participated in the Massachusetts Institute of Technology (MIT) COVID-19 Challenge in April assisting with UbiquiTest, a virtual platform that can advise healthcare professionals and companies on which populations can benefit from group testing. She’s also worked as a summer research intern at MIT and in the lab of Professor John Stoffolano, with whom she did her honors thesis. She has been a teaching assistant, a resident assistant, and an academic peer advisor over the course of her time at UMass. Palacios’s leadership extended to projects off campus as well, where she served as a tutor for Eureka! Girls Inc. in Holyoke. Her future plans include working as a research associate at MIT and eventually pursuing a Ph.D.
Two BMB undergrads named Rising Researchers
Two seniors in the Biochemistry and Molecular Biology Dept were named Rising Researchers by Research Next at UMass Amherst. Colin Lemire is a member of Sibongile Mafu’s lab, focusing on the biosynthesis of natural products (plants and fungi) to better understand their metabolic pathways to enable future research into their function and potential pharmaceutical applications. Joseph McGaunn works in Alexander Suvorov’s lab, where he investigates the role of molecular mechanisms in mediating interactions between an individual’s genetics and their environment, in transferring non-genetic information from one generation to the next, and the clinical applications for such mechanisms. The Rising Researcher program recognizes UMass Amherst undergraduate students who excel in research, scholarship and creative activity.
Alice Cheung receives 2020 Lawrence Bogorad Award for Excellence in Plant Biology Research
The American Society of Plant Biologists (ASPB) recently announced that BMB Professor Alice Cheung will receive the 2020 Lawrence Bogorad Award for Excellence in Plant Biology Research, made every other year to “a plant scientist whose work both illuminates the present and suggests paths to enlighten the future.” The award is named for Bogorad, Cheung’s postdoctoral mentor, for his contributions to plant biology that include bringing molecular biology techniques to bear on plant biology, groundbreaking research on chloroplast genetics, biogenesis, structure and function, and inspired teaching and mentoring. Along with the society’s international recognition, Cheung will receive a plaque and monetary award.
Peter Chien named an American Academy of Microbiology Fellow
The American Academy of Microbiology (AAM) recently honored BMB Professor Peter Chien by naming him to the 2020 class of Fellows of the Academy based on his record of “scientific achievement and original contributions that have advanced microbiology.” The AAM is the honored leadership group within the American Society of Microbiology (ASM), one of the oldest and largest scientific societies in the world.
Alice Cheung's publication in Nature explains how FERONIA helps plants avoid polyspermy
BMB Professor Alice Cheung is the senior author of a recent paper in Nature describing her team's discoveries surrounding FERONIA and how it helps flowering plants avoid polyspermy. Their research shows that FERONIA interacts with a sugar polymer called pectin to change the permeability of the cell wall and to trigger the presence of nitic oxide, both of which help deter sperm from entering the egg once it has been fertalized. Preventing polyspermy raises the chances of more females being fertilized and ensures better seed yields.